Abnormal 12-Hour Cyclic Gene Activity Found in Schizophrenic Brains
Jan. 24, 2023 Researchers present the first evidence of 12-hour cycles of gene activity in the human brain. The study also reveals that some of those 12-hour rhythms are missing or altered in the postmortem brains …
Actin Affects the Spread of Cancer in Several Ways
Jan. 24, 2023 The transport of molecules along the cell’s skeleton plays a role in cancer metastasis, researchers …
How Regulatory T Cells Halt Aberrant, Self-Reactive T Cells
Jan. 24, 2023 New research findings show in detail how self-reactive T cells — white blood cells dubbed Teffs that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or an …
New DNA Biosensor Could Unlock Powerful, Low-Cost Clinical Diagnostics
Jan. 24, 2023 By flagging disease-associated DNA biomarkers, medical professionals can make early diagnoses and provide personalized treatments, but the typical screening methods can be laborious, expensive or …
Co-Creating Health for Humanity: New Trends in Pharmaceutical Interorganizational Deals
Jan. 24, 2023 Discovering new drugs has become increasingly rare for independent large pharmaceutical companies in recent times. Almost 60% of new drugs are discovered through mergers and acquisitions and drug …
New Tool Uses Ultrasound ‘Tornado’ to Break Down Blood Clots
Jan. 23, 2023 Researchers have developed a new tool and technique that uses ‘vortex ultrasound’ — a sort of ultrasonic tornado — to break down blood clots in the brain. The new approach worked more …
Targeted Test for Antibiotic Resistance in Clinical Enterobacter Species
Jan. 23, 2023 Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide. Some of their representatives are highly resistant to commonly used …
Hypertension Drug Could Be Repurposed to Delay Aging, Animal Study Suggests
Jan. 23, 2023 Researchers have found that the drug rilmenidine can extend lifespan and slow …
Sweet Salvation — How a Sugar Cane Pathogen Is Gearing Up a New Era of Antibiotic Discovery
Jan. 23, 2023 A potent plant toxin with a unique way of killing harmful bacteria has emerged as one of the strongest new antibiotic candidates in …
Structural Insights Reveal How SPOP Protein Contributes to Cancer
Jan. 23, 2023 Scientists have captured the 3D structure of SPOP, revealing how mutations in previously unappreciated regions fuel …
Using a Seaweed Sugar to Trigger Immune Responses That Suppress Melanomas
Jan. 23, 2023 Researchers have identified a relatively natural way to increase the numbers and antitumor activities of TILs. A team demonstrates how L-fucose, a nontoxic dietary plant sugar that is enriched in red …
DNA Sequencing Method Lifts ‘Veil’ from Genome Black Box
Jan. 23, 2023 Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work — until …
A Soybean Protein Blocks LDL Cholesterol Production, Reducing Risks of Metabolic Diseases
Jan. 23, 2023 Soybean varieties with greater proportions of the protein B-conglycinin reduce plasma cholesterol levels and promote liver homeostasis, showing potential for preventing fatty liver disease and …
Dietary Nitrate — Found in Beetroot Juice — Significantly Increases Muscle Force During Exercise
Jan. 23, 2023 A new study has found that consuming dietary nitrate — the active molecule in beetroot juice — significantly increased muscle force while exercising. While it is known that dietary nitrate enhances …
Scientists Explain Emotional ‘Blunting’ Caused by Common Antidepressants
Jan. 22, 2023 Scientists have worked out why common anti-depressants cause around a half of users to feel emotionally ‘blunted’. They show that the drugs affect reinforcement learning, an important …
New Genetic Disorder That Causes Susceptibility to Opportunistic Infections
Jan. 21, 2023 Immunogeneticists have discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal …
Finding a New Way: Orienteering Can Train the Brain, May Help Fight Cognitive Decline
Jan. 20, 2023 The sport of orienteering, which draws on athleticism, navigational skills and memory, could be useful as an intervention or preventive measure to fight cognitive decline related to dementia, …
Regulating Immunological Memory May Help Immune System Fight Disease
Jan. 20, 2023 Scientists have long sought to better understand the human body’s immune responses that occur during various diseases, including cancer and inflammatory diseases. Scientists have now analyzed …
Female and Male Hearts Respond Differently to Stress Hormone in Mouse Study
Jan. 20, 2023 Female and male hearts respond differently to ‘fight or flight’ stress hormone, according to a new study in mice. It may help explain sex differences in arrhythmia …
Loneliness Associated With Unhealthful Diets and Physical Inactivity Among US College Students
Jan. 20, 2023 College students reporting a higher level of loneliness also reported a higher level of sedentary behavior and low …
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