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Wounds and Healing News — ScienceDaily

Trial Shows Benefits of Two Forms of Ankle Surgery for Osteoarthritis

Patients with advanced ankle osteoarthritis who undergo surgery see equally good outcomes from the two main surgical treatments for osteoarthritis, a new study has …

Immunotherapy Drug Did Not Increase Surgery Complications, Study Finds

Researchers recently published study results showing that administering immunotherapy drug pembrolizumab before surgery for oral cavity cancer did not increase rates of complication during and after …

Recovery from Muscle Loss Injuries Hindered by Immune Cell Conflicts

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice sheds light on …

Aggressive Warming During Surgery Does Not Reduce Major Complications

Patients kept at a body temperature of 37 C during major surgery had no fewer cardiac complications than patients kept at 35.5 C, according to new data. There were also no differences in the number …

Those With Facial Scars Rate Their Own Appearance More Critically Than Surgeons and Strangers

Patients who undergo facial surgery think their surgical scars look worse than surgeons and independent observers do, according to a new …

New Blood Clot Research Indicates Enhanced Understanding of Wound Repair

New research has revealed new information about how blood clots are formed during wound …

The Cellular Cleaning Program Autophagy Helps in Wound Healing

Scientists have shown that the recycling program of cells, autophagy, leads to the fusion of several single cells into multinucleated cell units during wound …

Three-Drug Combination Prolongs Survival in Men With Metastatic, Hormone-Sensitive Prostate Cancer

Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy …

Protein P53 Plays a Key Role in Tissue Repair, Study Finds

New research has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used by cells to repair tissues, and …

Light Therapy Fast-Tracks Healing of Skin Damage from Cancer Radiation Therapy

Light therapy may accelerate the healing of skin damage from radiation therapy by up to 50%, according to a recent …

Can We Go from Scarface to Scarless?

Researchers examined skin regeneration over two years in various body parts of the adult newt, Cynops pyrrhogaster. Their wounds were very quickly healed over several days without prolonged …

Defense or Repair: How Immune Cells Are Controlled During Wound Healing

Scientists show a causal link between tissue repair, mitochondrial metabolism, and the activation and function of macrophages (scavenger …

A Novel Protein Therapy for Efficient Skin Wound Healing

A protein named Agrin has been discovered to promote wound healing and repair, when it is triggered after skin tissue is injured. These findings could pave the way for the development of Agrin …

Printing Technique Creates Effective Skin Equivalent, Heals Wounds

Researchers have developed an approach to print skin equivalents, which may play a future role in facilitating the healing of chronic wounds. They used suspended layer additive manufacturing, …

Effectiveness of Ointment That Kills Antibiotic-Resistant Bacteria Shown

New research shows that use of a topical drug, called AB569, a combination of acidified nitrite and EDTA (or ethylenediaminetetraacetic acid) promotes killing of antibiotic-resistant bacteria while …

3D Printing of Blood Plasma May Speed Up Wound Healing

New research suggests that effective wound healing may be aided by replicating a crucial component of our …

‘Surgery Selfies’ Could Spot Serious Infections Early

Smartphone pictures of post-surgical wounds taken by patients and then assessed by clinicians can help with the early identification of infections, a study has …

Critical Role of Mechanosensor in Skin Wound Healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound …

Healing Skin Ischemia-Reperfusion Injuries With Interleukin-36 Receptor Antagonists

Skin wounds from ischemia-reperfusion injuries — tissue damage caused by blood returning to tissues after a period of oxygen deprivation — may not heal appropriately in some patients, owing to …

Genes May Affect the Level of Harmful Bacterial Toxins in the Bloodstream

Lipopolysaccharide, a virulence factor produced by bacteria, is a toxin that can cause a systemic inflammation via the circulation. In a recently completed study, genetic markers were discovered …

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Source link ScienceDaily recently covered a fascinating story related to wounds and the healing process: a groundbreaking investigation of how the immune system responds during the wound healing process. The study, conducted by researchers from the University of Massachusetts Medical School, revealed remarkable discoveries that could revolutionize the way doctors approach wound healing and repair.

The investigation focused on macrophage cells, which play an essential role in wound healing by responding to damaged tissue and initiating the healing process. What the research team found was that macrophage cells interact with other cell types in complex ways to activate a unique type of inflammatory response that is well-suited to healing.

This response, interestingly, is distinct from the typical immune system response to infection or other types of tissue damage. This suggests that a more focused approach to treating wounds might be necessary, in order to trigger that particular type of healing.

The study also revealed that the different types of macrophage cells respond differently to signals from damaged tissue. This means that pharmaceuticals with the potential to influence the healing process might not act in the same way on all types of macrophage cells.

Overall, this research has unveiled groundbreaking facts about the role the immune system plays in wound healing and thus provides valuable insight for future treatments. Wound healing and repair is an intricate and dynamic process, and this new information could help in the development of more effective therapies for treating wounds.

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